Deadpool is on the hunt for a superweapon with ties to his past - but every time he gets close, the armored brute named Thumper kind of...kills him. Wade Wilson always gets better, but dying still sucks. Can he and Domino get to the bottom of things before Deadpool meets his maker again? Answers might lay in a secret mission from years ago that brought Deadpool and X-Force together. But what do today's problems have to do with this firefight flashback? Garrison Kane, the cyborg called Weapon X, knows the truth about Thumper - and now it's up to Deadpool and Domino to beat it out of him!